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General-purpose AI agent that runs on your machine, with a desktop app, CLI and API. Written in Rust, works with 15+ model providers and connects to 70+ extensions via MCP. Originally from Block, now part of the Linux Foundation's AAIF.

Lets Claude Code push ML research forward unattended: literature review, topic selection, experiment deployment, cross-model review loops and paper writing through rebuttal, in 80+ skills. Codex acts as the independent reviewer by default; other model pairings work too.

ComfyUI's official CLI: install and launch ComfyUI in one step, manage custom nodes and model downloads, and run image and video workflows, with --json output on every command for agents. Can also submit jobs to paid Comfy Cloud.